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JCI standard abbreviations

Å, angstrom (10–8 cm)
Ab, antibody
AIDS, acquired immunodeficiency syndrome
ANOVA, analysis of variance
apo, apolipoprotein (apoB, apoE, etc.)
ATP, adenosine triphosphate (also ADP, AMP, cAMP, CTP, UDP, UTP, GMP, cGMP, etc.)

bp, base pair
BSA, bovine serum albumin
BTU, British thermal unit

°C, degrees Celsius
CFA, complete Freund’s adjuvant
CFC, colony-forming cell
CFU, colony-forming unit
Ci, curie(s)
CNS, central nervous system
cpm, counts per minute
CSA, colony-stimulating activity

D (delta), change in, change of
d, day(s)
d, density
Da, dalton(s) (use if unable to convert to kDa); kDa, kilodalton
DEAE, diethylaminoethyl
DMEM, Dulbecco’s modified Eagle’s medium
DMSO, dimethylsulfoxide
DNA, deoxyribonucleic acid (also cDNA, etc.)
DTT, dithiothreitol

ECM, extracellular matrix
ED50, 50% effective dose
EDTA, ethylenediaminetetraacetate
EGF, epidermal growth factor (also EGF-R, epidermal growth factor receptor)
EGTA, ethyleneglycol-bis (b-aminoethyl ether)-N,N’-tetraacetic acid
ELISA, enzyme-linked immunosorbent assay

°F, degrees Fahrenheit
FACS, registered trademark of Becton Dickinson and Co. (Franklin Lakes, New Jersey, USA) for a fluorescence-activated cell sorter
FBS, fetal bovine serum
Fc, crystallizable fragment (of immunoglobulin molecule)
FCS, fetal calf serum
FFA, free fatty acid
FGF, fibroblast growth factor (also bFGF, basic fibroblast growth factor)
FITC, fluorescein isothiocyanate
FMLP, formylmethionylleucylphenylalanine
ft, foot (feet)

g, gram(s)
g, unit of gravity
GAPDH, glyceraldehyde-3-phosphate dehydrogenase
G-CSF, granulocyte colony-stimulating factor
GFR, glomerular filtration rate
GM-CFU, granulocyte-macrophage colony-forming unit
GM-CSA, granulocyte-macrophage colony-stimulating activity
GM-CSF, granulocyte-macrophage colony-stimulating factor
g mol–1, molar mass
Gy, gray(s)

h, hour(s)
HBSS, Hanks’ balanced salt solution
HDL, high-density lipoprotein
HEPES, N-2-hydroxyethylpiperazine-N¢-2-ethane sulfonic acid
HGF, hepatocyte growth factor
HIV, human immunodeficiency virus (HIV-1, HIV-2, etc.)
HPLC, high-performance liquid chromatography
HSA, human serum albumin

IC50, inhibitory concentration of 50%
ICAM, intercellular adhesion molecule
ID50, 50% infective dose
IDL, intermediate-density lipoprotein
IFN, interferon
Ig, immunoglobulin (IgE, IgG, etc.)
IGF, insulin-like growth factor
IL, interleukin (IL-12, etc.)
in., inch(es)
IU, international unit(s)

°K, degrees kelvin
kb, kilobase
kcal, kilocalorie(s)
Kd, dissociation constant
KI, inhibition constant
Km, Michaelis constant

l, liter(s)
ml, microliter(s)
ml, milliliter(s)
LD50, 50% lethal dose
LDL, low-density lipoprotein
LPS, lipopolysaccharide

m, meter(s)
mm, micrometer(s) (micron[s]; 10–6 meters)
M, molar
mAb, monoclonal antibody
M-CSF, macrophage colony-stimulating factor
MEM, minimum essential medium
MHC, major histocompatibility complex
min, minute(s)
mmHg, millimeters of mercury
mo, month
moi, multiplicity of infection
mol, mole(s)
mol wt, molecular weight
Mops, 3-(4-morpholino) propane sulfonic acid
Mr, relative molecular mass

n, number in study, group
N, normal (concentration)
NA, not applicable
NAD, nicotinamide adenine dinucleotide (also NADH, NAPDH, etc.)
NF-
kB, nuclear factor kB
NIH, National Institutes of Health (Bethesda, Maryland, USA)
no., number

OCT, optimal cutting temperature (compound)
OD, optical density

P, probability
PAGE, polyacrylamide gel electrophoresis
PBMC, peripheral blood mononuclear cell
PBS, phosphate-buffered saline
PCR, polymerase chain reaction (also RT-PCR, reverse transcriptase-PCR)
PDGF, platelet-derived growth factor (also PDGF-R, platelet-derived growth factor receptor, etc.)
pH, hydrogen ion concentration
pI, isoelectric point
PIPES, piperazine-N,N
¢-bis(2-ethanesulfonic acid)
PMA, phorbol myristate acetate
PMSF, phenylmethylsulfonyl fluoride
PPAR, peroxisome proliferator–activated receptor
psi, pounds per square inch
PVDF, polyvinylidene difluoride

r, correlation coefficient
RANTES, regulated upon activation, normal T cell expressed and secreted (cytokine)
RFLP, restriction fragment length polymorphism
RIA, radioimmunoassay
RNA, ribonucleic acid (also mRNA, etc.)
rpm, revolution(s) per minute
RPMI, Roswell Park Memorial Institute medium

s, second(s)
SD, standard deviation
SDS, sodium dodecyl sulfate
SE, standard error
SEM, standard error of the mean
SSC, standard saline citrate

t1/2, half-life
TGF, transforming growth factor
Th, T helper (Th1 cell, etc.)
TLC, thin-layer chromatography
TNF, tumor necrosis factor
Tris, tris(hydroxymethyl)-aminomethane
TRITC, tetrarhodamine isothiocyanate
TUNEL, terminal deoxynucleotidyl transferase–mediated dUTP nick end-labeling

U, unit(s)

V, volt(s)
VCAM, vascular cell adhesion molecule
VEGF, vascular endothelial growth factor
VLDL, very-low-density lipoprotein
Vmax, maximum velocity
vWF, von Willebrand factor
vol, volume(s)

W, watt(s) (voltampere[s])
wk, week
wt, weight

yr, year


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